Christopher Wyatt

Position: Eco-Flow project lead (September 2023–present)

Current project: Building a bioinformatics ecosystem for ecologists using Nextflow.

Research interests: Building tools for fully reproducible data pipelines in ecological omics research. Using genomes, transcriptomes, proteomes and other research inputs, we build robust, tested, reproducible, scalable and easy-to-use data pipelines to speed up research output in our field, through the Eco-Flow project.

Other interests: Research into non-model organisms — wasps primarily — and their genomes.

Background

Sept 2023–present: Project lead (Eco-Flow)
2019–2022: Post-doctoral Research Assistant, University College London
2015–2019: PhD candidate, Centre for Genomic Regulation (CRG), Barcelona
2014–2015: MSc Biomedicine, Universitat Pompeu Fabra, Barcelona
2013–2014: Research assistant, Bristol University (Sumner lab)
2010–2011: MRes Biosystematics, Imperial College London
2006–2010: BSc Palaeobiology, University College London

Publications

Wyatt, C.D.R., Bentley, M.A., Taylor, D., Favreau, E., Brock, R.E., Taylor, B.A., Bell, E., Leadbeater, E., Sumner, S. (2023) Social complexity, life-history and lineage influence the molecular basis of castes in vespid wasps. Nature Communications 14(1). doi: 10.1038/s41467-023-36456-6
Wyatt, C.D.R., Pernaute, B., Gohr, A., Miret-Cuesta, M., Goyeneche, L., Rovira, Q., Salzer, M.C., Boke, E., Bogdanovic, O., Bonnal, S., Irimia, M. (2022) A developmentally programmed splicing failure contributes to DNA damage response attenuation during mammalian zygotic genome activation. Science Advances. doi: 10.1126/sciadv.abn4935
Wyatt, C.D.R., Bentley, M., Taylor, D., Favreau, E., Brock, R.E., Taylor, B.A., Bell, E., Leadbeater, E. & Sumner, S. (2021) Social complexity, life-history and lineage influence the molecular basis of caste in a major transition in evolution. bioRxiv. doi: 10.21203/rs.3.rs-835604/v1
Marlétaz, F., Firbas, P.N., Maeso, I., Tena, J.J., Bogdanovic, O., Perry, M., Wyatt, C.D.R., et al. (2018) Amphioxus functional genomics and the origins of vertebrate gene regulation. Nature. doi: 10.1038/s41586-018-0734-6
Kennedy, P., Baron, G., Qiu, B., Freitak, D., Helanterä, H., Hunt, E.R., Manfredini, F., et al. (2017) Deconstructing superorganisms and societies to address big questions in biology. Trends in Ecology and Evolution. doi: 10.1016/j.tree.2017.08.004
Maeso, I., Dunwell, T.L., Wyatt, C.D.R., Marlétaz, F., Vető, B., Bernal, J.A., Quah, S., Irimia, M., and Holland, P.W.H. (2016) Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals. BMC Biology 14(1): 45. doi: 10.1186/s12915-016-0267-0
Guillemin, M-L., Contreras-Porcia, L., Ramírez, M.E., Macaya, E.C., Bulboa Contador, C., Woods, H., Wyatt, C., and Brodie, J. (2016) The bladed Bangiales (Rhodophyta) of the South Eastern Pacific: molecular species delimitation reveals extensive diversity. Molecular Phylogenetics and Evolution 94(Pt B): 814–26. doi: 10.1016/j.ympev.2015.09.027
Giampietro, C., Deflorian, G., Gallo, S., Di Matteo, A., Pradella, D., Bonomi, S., Belloni, E., et al. (2015) The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nature Communications 6. doi: 10.1038/ncomms9479
Patalano, S., Vlasova, A., Wyatt, C., Ewels, P., Camara, F., Ferreira, P.G., Asher, C.L., et al. (2015) Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies. Proceedings of the National Academy of Sciences 112(45): 13970–75. doi: 10.1073/pnas.1515937112